氨基磺酸铵:一种“一锅法”合成3,4-二氢嘧啶-2(1H)-(硫)酮的有效催化剂

赵新海; 姬红; 刘晨江

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氨基磺酸铵:一种“一锅法”合成3,4-二氢嘧啶-2(1H)-(硫)酮的有效催化剂

研究精粹 | 更新时间：2026-01-21

- 氨基磺酸铵:一种“一锅法”合成3,4-二氢嘧啶-2(1H)-(硫)酮的有效催化剂
- 氨基磺酸铵:一种“一锅法”合成3,4-二氢嘧啶-2(1H)-(硫)酮的有效催化剂
- 新疆大学学报（自然科学版中英文） 2010年27卷第2期页码：132-135
- 作者机构：
  
  1. 新疆大学化学化工学院石油天然气精细化工教育部重点实验室
  2. 新疆大学理化测试中心
- 作者简介：
- 基金信息：
  
  国家自然科学基金(No:20662009)资助
- DOI：
  中图分类号： TQ254.1
- 纸质出版：2010
- 稿件说明：
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[1]赵新海,姬红,刘晨江.氨基磺酸铵:一种“一锅法”合成3,4-二氢嘧啶-2(1H)-(硫)酮的有效催化剂[J].新疆大学学报(自然科学版),2010,27(02):132-135.

赵新海, 姬红, 刘晨江. 氨基磺酸铵:一种“一锅法”合成3,4-二氢嘧啶-2(1H)-(硫)酮的有效催化剂[J]. Journal of Xinjiang University (Natural Science Edition in Chinese and English), 2010, 27(2): 132-135.
[1]赵新海,姬红,刘晨江.氨基磺酸铵:一种“一锅法”合成3,4-二氢嘧啶-2(1H)-(硫)酮的有效催化剂[J].新疆大学学报(自然科学版),2010,27(02):132-135. DOI：

赵新海, 姬红, 刘晨江. 氨基磺酸铵:一种“一锅法”合成3,4-二氢嘧啶-2(1H)-(硫)酮的有效催化剂[J]. Journal of Xinjiang University (Natural Science Edition in Chinese and English), 2010, 27(2): 132-135. DOI：

摘要

本文报道了氨基磺酸铵催化芳香醛、β-酮酯和脲或硫脲一锅法合成3

4-二氢嘧啶-2(1H)-(硫)酮的有效方法.与经典的Biginelli反应比较

该方法具有产率高、反应时间短且操作简便等优点.

Abstract

An efficient procedure for the one-pot Biginelli condensation reaction of aromatic aldehydes

β-ketoester and urea or thiourea employing NH_2SO_3NH4 as a novel catalyst is described.Compared with the classical Biginelli reaction conditions

the present method has the advantage of good yields

short reaction time and simplicity in the experimental procedure.

关键词

Keywords

references

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