objective: To assess the management mode of major scientific projects in military hospitals.Method: comprehensively analyzing the theoretical and practical experience summarized in the management procedures of the project of national scientific fund—"hemoglobinopathy study in the multi-ethnic areas along the Silk Road in China".Result: the concept of "3 control

3 management

1 organization and 1 coordination" was proposed in the project management mode

and some methods of "3 management" during the implementation of major project of scientific research were mainly presented in this paper.